MyFM's Rick Michaels - Massachusetts State Police say a deadly wrong-way crash on Route 495 Northbound occurred around 5:40 this morning and at this time all-lanes are now open to traffic. Initially described as a multi-vehicle crash approaching Exit 22 the Mass Pike on Route 495 Northbound. The female driver who was traveling Southbound on Route 495 Northbound was killed in the accident. She was pronounced dead at the scene. There has also been a report of the male driver of a pick-up truck suffered serious injuries but not life-threatening injuries and was taken to a Worcester Hospital. Massachusetts State Police say the facts and circumstances surrounding the crash remain under investigation. All three lanes northbound were shut down following the crash. All reopening shortly after eight o’clock this morning.